User:Abarrera

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Dr. Alessandra Barrera

Education

Grants and Awards

Publications

  • [1] Barrera, A., Fang, X., Jacob, J., Casey, E., Thiyagarajan, P., and Pan, T. Dimeric and monomeric Bacillus subtilis RNase P holoenzyme in the absence and presence of pre-tRNA substrates. Biochemistry 41, 12986-12994 (2002).
  • [2] Barrera, A and Pan, T. Interaction of the Bacillus subtilis RNase P with the 30S ribosomal subunit. RNA 10(3), 482-92 (2004).

Work Experience

  • Summer 2010 - Spring 2011 Assistant Professor, Biology Program, Georgia Gwinnett College, Lawrenceville, Georgia
    • Summer 2010 Courses:
      • Cell Biology
        • BIOL3400-01 - lecture/lab
      • Biology Internships
        • BIOL4800-01
      • Information Technology Internships
        • ITEC4900-01
    • Fall 2010 Courses:
      • Biological Sciences I
        • BIOL1101K-02 - lecture/lab
        • BIOL1101K-03 - lecture/lab
      • Principles of Biology I
        • BIOL1107K-02 - lecture/lab
      • Biology Internships - Emory Eastside students
        • BIOL4800-01
    • Spring 2011 Courses:
      • Principles of Biology I
        • BIOL1107K-03 - lecture/lab
      • Bioinformatics
        • BIOL4200-01 - lecture
        • BIOL4200-02 - lecture
      • Biology Internships - Emory Eastside students
        • BIOL4800-01
  • Summer 2009 - Spring 2010 Assistant Professor, Biology Program, Georgia Gwinnett College, Lawrenceville, Georgia
    • Summer 2009 Courses:
      • First Year Seminar course
        • GGC1000-02 - lecture
    • Fall 2009 Courses:
      • Biological Sciences I
        • BIOL1101K-06 - lecture/lab
      • Cell Biology
        • BIOL3400K-01 - lecture/lab
        • BIOL3400K-02 - lecture/lab
    • Spring 2010 Courses:
      • Biochemistry
        • BCHM3100K-01 - lecture/lab
        • BCHM3100K-02 - lecture/lab
  • Fall 2008- Spring 2009 Assistant Professor, Biology Program, Georgia Gwinnett College, Lawrenceville, Georgia
    • Fall 2008 Courses:
      • Biological Sciences I
        • BIOL1101-09 - lecture
        • BIOL1101L-09 - lab
        • BIOL1101-16 - lecture
        • BIOL1101L-16 - lab
      • Cell Biology
        • BIOL3400-01 - lecture
        • BIOL3400L-01 - lab
      • Internship
        • BIOL4800-01 -
    • Spring 2009 Courses:
      • Biological Sciences I
        • BIOL1101-04 - lecture
        • BIOL1101L-04 - lab
      • Bioinformatics
        • BIOL4200-01 - lecture
  • Summer 2008 Adjunct Faculty, Georgia Perimeter College, Lawrenceville, Georgia
      • Biological Sciences I
        • BIOL1402-360 - lecture
        • BIOL1402L-361 - lab
      • Principles of Biology I
        • BIOL2107-301 - lecture
  • Fall 2007- Spring 2008 Assistant Professor, Biology Program, Georgia Gwinnett College, Lawrenceville, Georgia
    • Fall 2007 Courses:
      • Biological Sciences I
        • BIOL1101-07 - lecture
        • BIOL1101L-07 - lab
        • BIOL1101-11 - lecture
        • BIOL1101L-11 - lab
      • Freshman Experience Seminar
        • GGC1000-40
    • Spring 2008 Courses:
      • Biological Sciences I
        • BIOL1101-03 - lecture
        • BIOL1101L-03 - lab
      • Cell Biology
        • BIOL3400 - lecture
        • BIOL3400L - lab
  • Fall 2005 Fellowship Instructor, Spelman College Atlanta, Georgia
    • Course:
      • Physiolocy of Human Nutrition - upperdivision elective for majors
        • BIO491E
  • Spring 2005 Lecturer for FIRST program "Class within a Class" Atlanta, Georgia
  • Spring 2004 Instructor and developer Teaching Assistant Training Program at University of Chicago Chicago, Illinois
  • Spring 2003 Instructor and developer Teaching Assistant Training Program at University of Chicago Chicago, Illinois
  • Winter 2002 Guest Lecturer in Undergraduate Course at Teaching University of Chicago Chicago, Illinois
    • Course:
      • Molecular Biolgy - undergraduate course for majors
        • BIOS244

Oral Presentations

  • 2005 Teaching Development Course Topic:”Sex vs. Gender” Emory University Atlanta, Georgia
  • 2004 Dissertation Defense Topic: “Characterization of the Bacillus subtilis Ribonuclease P holoenzyme dimer” [http://www.uchicago.edu/ University of Chicago, Chicago, Illinois
  • 2003 University of Chicago Molecular Biosciences Annual Retreat Topic: “Interaction of the Bacillus subtilis RNase P with the 30S ribosomal subunit” University of Chicago Chicago, Illinois
  • 2003 NIH Molecular and Cellular Biology training grant symposium Topic: “Interaction of the Bacillus subtilis RNase P with the 30S ribosomal subunit” University of Chicago Chicago, Illinois
  • 2000 St. Edward's University Natural Sciences Symposium - Alumni Speaker Topic: “Science Career Pathway: Entering Graduate School” St. Edward's University Austin, Texas
  • 1999 St Edwards University Natural Sciences Symposium - Undergraduate presenter Topic: “Design and Methodology of Recombinant Methods of production of Serine Carboxypeptidase II” St. Edward's University Austin, Texas

Poster Presentations

  • 2006 Torres, M., Aguilar-Roca, N., Barrera, A., Juarez, M., Rudati, J., Vidal Pizarro, I., Vigerust, D., Ceballos Yoshida, L., and A. Roca. "The SACNAS Postdoc Committee as a model for diversifying the science workforce" National SACNAS Conference Tampa, Florida
  • 2006 Barrera, A., Delgado-Reyes, C., and McGinnis, G. “Using Games to promote engagement and reinforce learning” IRACDA Annual Meeting Kansas City, Missouri
  • 2006 Delgado-Reyes, C., Barrera, A., and McGinnis, G. “Assessing and Reinforcing Learning of Complex Metabolic Processes” IRACDA Annual Meeting Kansas City, Missouri
  • 2006 Pilgrim, M.J., and Barrera, A. “FIRST 101: A Blackboard “Course” for New (and Old) Fellows in the FIRST program” IRACDA Annual Meeting Kansas City, Missouri
  • 2006 Torres, M., Aguilar-Roca, N., Barrera, A., Juarez, M., Rudati, J., Vidal Pizarro, I., Vigerust, D., Ceballos Yoshida, L., and A. Roca. "The SACNAS Postdoc Committee as a model for diversifying the science workforce" National Postdoctoral Association 4th Annual Conference Bethesda, Maryland
  • 2003 Barrera, A. and Pan, T. “Interaction of the Bacillus subtilis RNase P with the 30S ribosomal subunit” RNA Society International Meeting Vienna, Austria
  • 2002 Barrera, A., Fang, X., Jacob, J., Casey, E., Thiyagarajan, P., and Pan, T. Dimeric and monomeric Bacillus subtilis RNase P holoenzyme in the absence and presence of pre-tRNA substrates. University of Chicago Molecular Biosciences Annual Retreat
  • 2002 Barrera, A., Fang, X., Jacob, J., Casey, E., Thiyagarajan, P., and Pan, T. “Dimeric and monomeric Bacillus subtilis RNase P holoenzyme in the absence and presence of pre-tRNA substrates” Society for the Advancement of Chicanos and Native Americans in Science (SACNAS) Anaheim, California
  • 1999 Barrera, A., Hunter, A., Healy, E., and Kopecki-Fjetland, M. “A Stepwise methodology for Recombinant production of proteins in the Undergraduate Laboratory” Paper CHED 109 218th American Chemical Society National Meeting New Orleans, Louisiana
  • 1999 Alessandra Barrera, Hendrix, J., Barrera, A., Healy, E., and Kopecki-Fjetland, M. “Design and Methodology of Recombinant Methods of production of Serine Carboxypeptidase II” 217th http://www.acs.org/ American Chemical Society]National Meeting Anaheim, California

Professional Memberships

  • Society for the Advancement of Native Americans and Chicanos in Science - Life Member (SACNAS)
  • National Science Teachers Association (NSTA)
  • American Association for the Advancement of Science (AAAS)
  • American Society for Cell Biology (ASCB)
  • American Institute of Biological Sciences (AIBS)
  • Association for Women in Science (AWIS)
  • Georgia Academy of Science (GAS)
  • Latin American Association (LAA)

Research Experience

  • June 2004 - present Postdoctoral Fellow: Emory University School of Medicine, Department of Microbiology and Immunology, Atlanta, Georgia
    • Advisor: Tony Romeo
    • Funded by: NIH NIGMS IRACDA Grant
    • Project: Csr (carbon storage regulator) is a global regulatory system that controls bacterial gene expression post-transcriptionally. Its effector is a small RNA-binding protein referred to as CsrA. CsrA regulates central carbon flux, biofilm formation and motility in Escherichia coli. My research focus is to characterize the structure of the CsrA protein and the specific binding interactions to one of its RNA substrates (CsrB).
  • August 1999 - June 2004 Graduate Research Student: University of Chicago, Chicago, Illinois, Biochemistry and Molecular Biology Department, Biological Sciences Division
    • Advisor: Tao Pan
    • Funded by: NIH Minority Research Grant, NIH Training Grants
    • Project: Ribonuclease P (RNaseP) is a universally conserved endonuclease (ribozyme) required for the 5’ maturation of tRNA. Besides the ribosome, RNase P is the only other ribozyme identified to date that is present in all organisms. RNase P was shown to be functioning as a dimer rather than a monomer as once thought. Therefore, my thesis research elucidated the structure and function of the RNase P monomer and dimer in Bacillus subtilis. My graduate also demonstrated that the RNase P holoenzyme dimer forms a specific complex with the 30S ribosomal subunit. Formation of the RNase P–30S complex requires the RNase P protein and involves a conserved region near the active site of the RNase P RNA.
  • September 1996 - August 1999 Undergraduate Research Assistant: St. Edward’s University, Department of Chemistry, Austin, Texas
    • Advisor: Henry Altmiller and Mary Kopecki-Fjetland
    • Funded by: Welch Scholar Support Program
    • Project: An enzyme, serine carboxypeptidase II, contains an active site with a catalytic triad similar to that of the serine proteases but whose folding topology is very similar in structure to that of carboxypeptidase A, hence the name. The project was to design a recombinant DNA technology to express the protein in vivo so as to study the various aspects of its structure and activity. This project raised very interesting questions regarding structure-activity relationships and the possibility of independent or convergent evolutionary schemes for these enzymes.

Contact Information

  • Phone: 678-407-5751 (office)
  • Email: abarrera@ggc.usg.edu
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